Nigella Sativa's Effect on Biochemical as well as Anthropometric Parameters in Diabetic Rats on High Fat Diet

Objective: Black cumin (Nigella sativa L.) seeds and its crude extract or essential oils have been widely used traditionally for nutritional medicinal applications in Asian countries. Its effects on diabetics with high fat diet consumption not adequately studied. This study was undertaken to body weight, abdominal girth, lipid profile plasma glucose levels diabetic fed rats. Materials Methods : Streptozotocin induced male Wistar rats were [5130 kcal] 4 weeks after which they given vehicle, Nigella ethanolic (300mg/kg), (600 mg) metformin (100 mg). Lipid profile, blood glucose, weight & girth measured. Results: caused significant reduction total cholesterol, triglycerides, VLDL non HDL cholesterol comparable metformin. Conclusion shows anti-hyperglycemic improvement is Further studies are required advocate use patients diabetes dyslipidemias. Keywords: sativa, mellitus, antihyperlipidemic, antihyperglycemic,